Sunny Shin, Ph.D.
Associate Professor of Microbiology
University of Pennsylvania
Title of the talk:
Innate immune defense against intracellular bacterial pathogens
Dr. Sunny Shin received her Bachelor’s in Biology from the Massachusetts Institute of Technology (MIT) in 1998 and her Ph.D. in Microbiology & Immunology from Stanford in 2004. Upon completion of her postdoctoral research, Dr. Shin relocated to the University of Pennsylvania and has been at Penn ever since.
Dr. Shin’s research lies at the interface of the relationship between microbial pathogens and their hosts. One arm of her research focuses on how the immune system detects microbial pathogens and a complementary project explores how microbial pathogens evade the immune system. More specifically, her research investigates the mammalian multiprotein complex called Inflammasome that plays an important role in distinguishing virulent bacteria from their avirulent counterparts by specifically recognizing virulence factors. In response to these factors, the infected host cell produces cell-to-cell signaling molecules that play an important role in host defense by counteracting the ability of pathogens from suppressing the immune system. The discoveries made herein have profound ramifications from furthering our understanding of bacterial pathogenesis to the development of prophylactic and therapeutic interventional strategies.
The keynote address is free and open to the public.